Burkholderia cenocepacia J2315, BCAL2739 (fusA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2739
NCBI Locus TagQU43_RS50315
Name
fusA
Replicon chromosome 1
Genomic location 3009400 - 3011511 (+ strand)

Cross-References

RefSeq WP_006490896.1
GI 206561077
Entrez 6932755
GI 206561077
INSDC CAR53040.1
NCBI Locus Tag QU43_RS50315
NCBI Old Locus Tag BCAL2739
RefSeq WP_006490896.1,GeneID
UniParc UPI00017B9865
UniProtKB Acc B4E912
UniProtKB ID B4E912_BURCJ
UniRef100 UniRef100_B4E912
UniRef50 UniRef50_Q9SI75
UniRef90 UniRef90_Q1BU86

Product

Feature Type CDS
Coding Frame 1
Product Name
elongation factor G
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -21.18
Kyte-Doolittle Hydrophobicity Value -0.311
Molecular Weight (kDa) 77653.0
Isoelectric Point (pI) 5.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000255 (1306 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2739
Search term: fusA

Human Homologs

Ensembl 97, assembly GRCh38.p12
G elongation factor mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:13780]
E-value: 3.9e-152
Percent Identity: 44.3

References

Chaperone properties of bacterial elongation factor EF-G and initiation factor IF2.
Caldas T, Laalami S, Richarme G
J Biol Chem 2000 Jan 14;275(2):855-60
PubMed ID: 10625618
Chlorobenzoate inhibits growth and induces stress proteins in the PCB-degrading bacterium Burkholderia xenovorans LB400.
Martínez P, Agulló L, Hernández M, Seeger M
Arch Microbiol 2007 Sep;188(3):289-97
PubMed ID: 17522847