Burkholderia cenocepacia J2315, BCAL2409 (dnaE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2409
NCBI Locus TagQU43_RS48715
Name
dnaE
Replicon chromosome 1
Genomic location 2665987 - 2669520 (- strand)

Cross-References

RefSeq WP_006489624.1
GI 206560768
Entrez 6933849
GI 206560768
INSDC CAR52710.1
NCBI Locus Tag QU43_RS48715
NCBI Old Locus Tag BCAL2409
RefSeq WP_006489624.1,GeneID
UniParc UPI00017B985F
UniProtKB Acc B4E6D5
UniProtKB ID B4E6D5_BURCJ
UniRef100 UniRef100_B4E6D5
UniRef50 UniRef50_Q9JXZ2
UniRef90 UniRef90_A3N7C5

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA polymerase III subunit alpha
Synonyms DnaE
Evidence for Translation
Charge (pH 7) -19.19
Kyte-Doolittle Hydrophobicity Value -0.280
Molecular Weight (kDa) 130474.2
Isoelectric Point (pI) 5.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002198 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2409
Search term: dnaE

References

Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B.
Ortega X, Silipo A, Saldías MS, Bates CC, Molinaro A, Valvano MA
J Biol Chem 2009 Aug 7;284(32):21738-51
PubMed ID: 19525227