Burkholderia cenocepacia J2315, BCAL2407 (wabS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2407
NCBI Locus TagQU43_RS48705
Name
wabS
Replicon chromosome 1
Genomic location 2663070 - 2664134 (- strand)

Cross-References

RefSeq WP_012492745.1
GI 206560766
Entrez 6932479
GI 206560766
INSDC CAR52708.1
NCBI Locus Tag QU43_RS48705
NCBI Old Locus Tag BCAL2407
RefSeq WP_012492745.1,GeneID
UniParc UPI00017B985D
UniProtKB Acc B4E6D3
UniProtKB ID B4E6D3_BURCJ
UniRef100 UniRef100_U1XRR9
UniRef50 UniRef50_B3R3A3
UniRef90 UniRef90_A0A095DSN8

Product

Feature Type CDS
Coding Frame 1
Product Name
putative glycosyltransferase
Product Name Confidence: Class 1
Synonyms WabS
Evidence for Translation
Charge (pH 7) 7.02
Kyte-Doolittle Hydrophobicity Value -0.078
Molecular Weight (kDa) 38729.9
Isoelectric Point (pI) 8.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 263 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006142 (381 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2407
Search term: wabS

Human Homologs

References

Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B.
Ortega X, Silipo A, Saldías MS, Bates CC, Molinaro A, Valvano MA
J Biol Chem 2009 Aug 7;284(32):21738-51
PubMed ID: 19525227