Burkholderia cenocepacia J2315, BCAL2402 (wabO)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2402
NCBI Locus TagQU43_RS48675
Name
wabO
Replicon chromosome 1
Genomic location 2657099 - 2657869 (+ strand)

Cross-References

RefSeq WP_006489606.1
GI 206560761
Entrez 6932474
GI 206560761
INSDC CAR52703.1
NCBI Locus Tag QU43_RS48675
NCBI Old Locus Tag BCAL2402
RefSeq WP_006489606.1,GeneID
UniParc UPI00017B9858
UniProtKB Acc B4E6C8
UniProtKB ID B4E6C8_BURCJ
UniRef100 UniRef100_A0A095FYR0
UniRef50 UniRef50_A0A095FYR0
UniRef90 UniRef90_A0A095FYR0

Product

Feature Type CDS
Coding Frame 1
Product Name
putative LPS biosynthesis-related protein
Product Name Confidence: Class 1
Synonyms WabO
Evidence for Translation
Charge (pH 7) 2.86
Kyte-Doolittle Hydrophobicity Value -0.091
Molecular Weight (kDa) 28280.6
Isoelectric Point (pI) 8.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 360 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002194 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2402
Search term: wabO

Human Homologs

References

Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B.
Ortega X, Silipo A, Saldías MS, Bates CC, Molinaro A, Valvano MA
J Biol Chem 2009 Aug 7;284(32):21738-51
PubMed ID: 19525227