Burkholderia cenocepacia J2315, BCAL2386

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2386
NCBI Locus TagQU43_RS48595
Name
Replicon chromosome 1
Genomic location 2642496 - 2643275 (- strand)

Cross-References

RefSeq WP_006481870.1
GI 206560745
Entrez 6933820
GI 206560745
INSDC CAR52687.1
NCBI Locus Tag QU43_RS48595
NCBI Old Locus Tag BCAL2386
RefSeq WP_006481870.1,GeneID
UniParc UPI00017B9819
UniProtKB Acc B4E5R4
UniProtKB ID B4E5R4_BURCJ
UniRef100 UniRef100_A0A095EP82
UniRef50 UniRef50_D8NRU8
UniRef90 UniRef90_Q0BD87

Product

Feature Type CDS
Coding Frame 1
Product Name
putative dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -3.70
Kyte-Doolittle Hydrophobicity Value 0.166
Molecular Weight (kDa) 26680.0
Isoelectric Point (pI) 5.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5IDY OXIDOREDUCTASE 02/24/16 Crystal structure of an oxidoreductase from Burkholderia vietnamiensis in complex with NADP BURKHOLDERIA VIETNAMIENSIS (STRAIN G4 / LMG 22486) 1.85 X-RAY DIFFRACTION 94.6
5VPS OXIDOREDUCTASE 05/05/17 Crystal structure of an SDR from Burkholderia ambifaria in complex with NADPH with a TCEP adduct BURKHOLDERIA AMBIFARIA (STRAIN MC40-6) 1.45 X-RAY DIFFRACTION 96.1
5IDX OXIDOREDUCTASE 02/24/16 Crystal structure of an oxidoreductase from Burkholderia vietnamiensis BURKHOLDERIA VIETNAMIENSIS (STRAIN G4 / LMG 22486) 1.95 X-RAY DIFFRACTION 94.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002177 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2386

Human Homologs

Ensembl 97, assembly GRCh38.p12
retinol dehydrogenase 13 [Source:HGNC Symbol;Acc:HGNC:19978]
E-value: 7.0e-06
Percent Identity: 28.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
retinol dehydrogenase 13 [Source:HGNC Symbol;Acc:HGNC:19978]
E-value: 7.0e-06
Percent Identity: 28.1

References

No references are associated with this feature.