Burkholderia cenocepacia J2315, BCAL2248 (pobA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2248
NCBI Locus TagQU43_RS47865
Name
pobA
Replicon chromosome 1
Genomic location 2491483 - 2492238 (- strand)

Cross-References

RefSeq WP_006488091.1
GI 206560609
Entrez 6933651
GI 206560609
INSDC CAR52549.1
NCBI Locus Tag QU43_RS47865
NCBI Old Locus Tag BCAL2248
RefSeq WP_006488091.1,GeneID
UniParc UPI00017B9661
UniProtKB Acc B4EDX7
UniProtKB ID B4EDX7_BURCJ
UniRef100 UniRef100_B4EDX7
UniRef50 UniRef50_Q2SXJ8
UniRef90 UniRef90_Q27IP6

Product

Feature Type CDS
Coding Frame 1
Product Name
4'-phosphopantetheinyl transferase superfamily protein
Product Name Confidence: Class 1
Synonyms Group I Sfp-type phosphopantetheinyl transferase, PobA
Evidence for Translation
Charge (pH 7) 2.11
Kyte-Doolittle Hydrophobicity Value 0.115
Molecular Weight (kDa) 26304.5
Isoelectric Point (pI) 8.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 182 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002067 (644 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2248
Search term: pobA

Human Homologs

Ensembl 97, assembly GRCh38.p12
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Source:HGNC Symbol;Acc:HGNC:14235]
E-value: 4.0e-06
Percent Identity: 26.3

References

The pobA gene of Burkholderia cenocepacia encodes a group I Sfp-type phosphopantetheinyltransferase required for biosynthesis of the siderophores ornibactin and pyochelin.
Asghar AH, Shastri S, Dave E, Wowk I, Agnoli K, Cook AM, Thomas MS
Microbiology 2011 Feb;157(Pt 2):349-361
PubMed ID: 20966087