Burkholderia cenocepacia J2315, BCAL2157 (suhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2157
NCBI Locus TagQU43_RS47400
Name
suhB
Replicon chromosome 1
Genomic location 2382131 - 2382934 (+ strand)

Cross-References

RefSeq WP_006493635.1
GI 206560520
Entrez 6932290
GI 206560520
INSDC CAR52459.1
NCBI Locus Tag QU43_RS47400
NCBI Old Locus Tag BCAL2157
RefSeq WP_006493635.1,GeneID
UniParc UPI00017B9531
UniProtKB Acc B4ED80
UniProtKB ID B4ED80_BURCJ
UniRef100 UniRef100_B4ED80
UniRef50 UniRef50_Q3JQS8
UniRef90 UniRef90_B4ED80

Product

Feature Type CDS
Coding Frame 1
Product Name
SuhB
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.38
Kyte-Doolittle Hydrophobicity Value -0.216
Molecular Weight (kDa) 29504.1
Isoelectric Point (pI) 5.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 565 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001977 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2157
Search term: suhB
Search term: SuhB

Human Homologs

Ensembl 97, assembly GRCh38.p12
inositol monophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:6050]
E-value: 2.0e-35
Percent Identity: 32.9
Ensembl 97, assembly GRCh38.p12
inositol monophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:6050]
E-value: 2.0e-35
Percent Identity: 32.9

References

The suhB gene of Burkholderia cenocepacia is required for protein secretion, biofilm formation, motility and polymyxin B resistance.
Rosales-Reyes R, Saldías MS, Aubert DF, El-Halfawy OM, Valvano MA
Microbiology 2012 Sep;158(Pt 9):2315-2324
PubMed ID: 22767545