Burkholderia cenocepacia J2315, BCAL1688 (orbS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL1688
NCBI Locus TagQU43_RS44960
Name
orbS
Synonym: ecfI
Replicon chromosome 1
Genomic location 1846454 - 1847122 (+ strand)

Cross-References

RefSeq WP_006486089.1
GI 206560050
Entrez 6931944
GI 206560050
INSDC CAR51986.1
NCBI Locus Tag QU43_RS44960
NCBI Old Locus Tag BCAL1688
RefSeq WP_006486089.1,GeneID
UniParc UPI00017B928D
UniProtKB Acc B4E986
UniProtKB ID B4E986_BURCJ
UniRef100 UniRef100_Q2PZW3
UniRef50 UniRef50_G0A925
UniRef90 UniRef90_U2GZZ5

Product

Feature Type CDS
Coding Frame 1
Product Name
extracytoplasmic-function sigma-70 factor
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfI
Evidence for Translation
Charge (pH 7) 2.26
Kyte-Doolittle Hydrophobicity Value -0.231
Molecular Weight (kDa) 24623.8
Isoelectric Point (pI) 7.85

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 113 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001452 (638 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL1688
Search term: orbS

Human Homologs

References

PubMed ID: 17784978
The ornibactin biosynthesis and transport genes of Burkholderia cenocepacia are regulated by an extracytoplasmic function sigma factor which is a part of the Fur regulon.
Agnoli K, Lowe CA, Farmer KL, Husnain SI, Thomas MS
J Bacteriol 2006 May;188(10):3631-44
PubMed ID: 16672617