Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAL1676
|
NCBI Locus Tag | QU43_RS44905 |
Name |
|
Replicon | chromosome 1 |
Genomic location | 1833175 - 1834638 (+ strand) |
Comment | Member of rnd-3 operon encoding Resistance-Nodulation-Cell Division (RND) efflux pump RND-3 |
Comment | |
Comment | Major RND-3 substrates are nalidixic acid, ciprofloxacin, tobramycin, chlorhexidine |
RefSeq | YP_002230802.1 |
GI | 206560038 |
Entrez | 6933296 |
GI | 206560038 |
INSDC | CAR51974.1 |
NCBI Locus Tag | QU43_RS44905 |
NCBI Old Locus Tag | BCAL1676 |
RefSeq | YP_002230802.1 |
UniParc | UPI00017B9282 |
UniProtKB Acc | B4E8U8 |
UniProtKB ID | B4E8U8_BURCJ |
UniRef100 | UniRef100_B4E8U8 |
UniRef50 | UniRef50_A6V6E6 |
UniRef90 | UniRef90_A0K799 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
RND-3 efflux system outer membrane protein
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -0.05 |
Kyte-Doolittle Hydrophobicity Value | -0.042 |
Molecular Weight (kDa) | 52110.0 |
Isoelectric Point (pI) | 6.98 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 295 genera
|
Burkholderia Ortholog Group |
BG001445 (1160 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAL1676
Search term: RND-3 efflux system outer membrane protein
|
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance.
Buroni S, Pasca MR, Flannagan RS, Bazzini S, Milano A, Bertani I, Venturi V, Valvano MA, Riccardi G
BMC Microbiol 2009 Sep 17;9:200
PubMed ID: 19761586
|
Efflux pump-mediated drug resistance in Burkholderia.
Podnecky NL, Rhodes KA, Schweizer HP
Front Microbiol 2015;6:305
PubMed ID: 25926825
|