Burkholderia cenocepacia J2315, BCAL0535 (rqpS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0535
NCBI Locus TagQU43_RS39240
Name
rqpS
Replicon chromosome 1
Genomic location 587393 - 588208 (- strand)

Cross-References

RefSeq WP_006482035.1
GI 206558936
Entrez 6931029
GI 206558936
INSDC CAR50845.1
NCBI Locus Tag QU43_RS39240
NCBI Old Locus Tag BCAL0535
RefSeq WP_006482035.1,GeneID
UniParc UPI00017B9001
UniProtKB Acc B4E8H8
UniProtKB ID B4E8H8_BURCJ
UniRef100 UniRef100_B4E8H8
UniRef50 UniRef50_A2VUN0
UniRef90 UniRef90_A2VUN0

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component regulatory system, sensor histidine kinase RqpS
Product Name Confidence: Class 2
Synonyms sensor kinase protein
Evidence for Translation
Charge (pH 7) 4.32
Kyte-Doolittle Hydrophobicity Value -0.007
Molecular Weight (kDa) 28038.1
Isoelectric Point (pI) 8.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 396 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002879 (634 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0535
Search term: rqpS

Human Homologs

References

A novel two-component system modulates quorum sensing and pathogenicity in Burkholderia cenocepacia.
Cui C, Yang C, Song S, Fu S, Sun X, Yang L, He F, Zhang LH, Zhang Y, Deng Y
Mol Microbiol 2018 Apr;108(1):32-44
PubMed ID: 29363827