Burkholderia cenocepacia J2315, BCAL0352

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0352
NCBI Locus TagQU43_RS38295
Name
Synonym: bcsA
Replicon chromosome 1
Genomic location 383182 - 384027 (- strand)
CommentPart of the T6SS gene cluster

Cross-References

RefSeq WP_006488977.1
GI 206558758
Entrez 6930896
GI 206558758
INSDC CAR50662.1
NCBI Locus Tag QU43_RS38295
NCBI Old Locus Tag BCAL0352
RefSeq WP_006488977.1,GeneID
UniParc UPI00017B9130
UniProtKB Acc B4E6S4
UniProtKB ID B4E6S4_BURCJ
UniRef100 UniRef100_B4E6S4
UniRef50 UniRef50_C5AA76
UniRef90 UniRef90_A9AJ86

Product

Feature Type CDS
Coding Frame 1
Product Name
subfamily M15C metalopeptidase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 10.44
Kyte-Doolittle Hydrophobicity Value -0.109
Molecular Weight (kDa) 31344.0
Isoelectric Point (pI) 10.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 27 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000379 (642 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0352

References

A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
Anchoring the type VI secretion system to the peptidoglycan: TssL, TagL, TagP... what else?
Aschtgen MS, Thomas MS, Cascales E
Virulence 2010 Nov-Dec;1(6):535-40
PubMed ID: 21178498
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149