Burkholderia cenocepacia J2315, BCAL0323 (tatA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0323
NCBI Locus Tag	QU43_RS38145
Name	tatA
Replicon	chromosome 1
Genomic location	352214 - 352444 (+ strand)
Comment	Required for growth in the presence of 20__M CuSO4 (PMID:32090500)

Cross-References

RefSeq	WP_006477115.1
GI	206558729
Entrez	6930874
GI	206558729
INSDC	CAR50633.1
NCBI Locus Tag	QU43_RS38145
NCBI Old Locus Tag	BCAL0323
RefSeq	WP_006477115.1,GeneID
UniParc	UPI000052EADD
UniProtKB Acc	B4E646
UniProtKB ID	TATA_BURCJ
UniRef100	UniRef100_Q1BS36
UniRef50	UniRef50_Q2SUB3
UniRef90	UniRef90_Q2SUB3

Product

Feature Type	CDS
Coding Frame	1
Product Name	twin arginine translocase protein A Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	2.22
Kyte-Doolittle Hydrophobicity Value	-0.168
Molecular Weight (kDa)	8123.3
Isoelectric Point (pI)	10.03

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 200 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000344 (656 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0323 Search term: tatA Search term: twin arginine translocase protein A

Human Homologs

References

Copper resistance genes of Burkholderia cenocepacia H111 identified by transposon sequencing. Higgins S, Gualdi S, Pinto-Carbó M, Eberl L Environ Microbiol Rep 2020 Apr;12(2):241-249 PubMed ID: 32090500