Burkholderia cenocepacia J2315, BCAL0274 (mrcA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0274
NCBI Locus TagQU43_RS37900
Name
mrcA
Replicon chromosome 1
Genomic location 300917 - 303304 (- strand)

Cross-References

RefSeq YP_002229440.1
GI 206558680
Entrez 6933463
GI 206558680
INSDC CAR50584.1
NCBI Locus Tag QU43_RS37900
NCBI Old Locus Tag BCAL0274
RefSeq YP_002229440.1
UniParc UPI00017B9044
UniProtKB Acc B4E5Z7
UniProtKB ID B4E5Z7_BURCJ
UniRef100 UniRef100_B4E5Z7
UniRef50 UniRef50_Q7NZT7
UniRef90 UniRef90_G7H9G0

Product

Feature Type CDS
Coding Frame 1
Product Name
penicillin-binding protein 1A
Product Name Confidence: Class 1
Synonyms Class A penicillin-binding protein
Evidence for Translation
Charge (pH 7) 1.60
Kyte-Doolittle Hydrophobicity Value -0.232
Molecular Weight (kDa) 87110.2
Isoelectric Point (pI) 7.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 560 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000296 (1307 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0274
Search term: mrcA

References

Expression and characterization of penicillin-binding proteins in Burkholderia cenocepacia.
Specht KM, Sheetz KH, Alexander CM, Lamech LT, O'Connor LH, Walker DM, Stevenson HP
Curr Microbiol 2010 Apr;60(4):274-9
PubMed ID: 19924480