Burkholderia pseudomallei 1710b, BURPS1710b_A0593 (orgB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 1710b
GCF_000012785.1|latest
Locus Tag
BURPS1710b_A0593
NCBI Locus TagBURPS1710B_RS21435
Name
orgB
Replicon chromosome II
Genomic location 784874 - 785668 (+ strand)

Cross-References

RefSeq WP_004528829.1
GI 76817633
Entrez 3694068
GI 76817633
INSDC ABA51580.1
NCBI Locus Tag BURPS1710B_RS21435
NCBI Old Locus Tag BURPS1710b_A0593
RefSeq WP_004528829.1
UniParc UPI000055A7B2
UniProtKB Acc Q3JL01
UniProtKB ID Q3JL01_BURP1
UniRef100 UniRef100_Q3JL01
UniRef50 UniRef50_Q2T731
UniRef90 UniRef90_A3NLF7

Product

Feature Type CDS
Coding Frame 1
Product Name
Oxygen-regulated invasion protein OrgB
Product Name Confidence: Class 2
Synonyms type III secretion system protein
Evidence for Translation
Charge (pH 7) -2.67
Kyte-Doolittle Hydrophobicity Value -0.316
Molecular Weight (kDa) 28241.1
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 4 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG020947 (286 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS1710b_A0593
Search term: orgB

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592