Burkholderia pseudomallei 1710b, BURPS1710b_A0589 (bsaM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 1710b
GCF_000012785.1|latest
Locus Tag
BURPS1710b_A0589
NCBI Locus TagBURPS1710B_RS21410
Name
bsaM
Replicon chromosome II
Genomic location 781455 - 782741 (+ strand)

Cross-References

RefSeq WP_004528825.1
GI 76818491
Entrez 3692619
GI 76818491
INSDC ABA52438.1
NCBI Locus Tag BURPS1710B_RS21410
NCBI Old Locus Tag BURPS1710b_A0589
RefSeq WP_004528825.1
UniParc UPI00005C38B9
UniProtKB Acc Q3JL05
UniProtKB ID Q3JL05_BURP1
UniRef100 UniRef100_A0A069BE22
UniRef50 UniRef50_A3MCF1
UniRef90 UniRef90_A3MCF1

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein PrgH/EprH
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.90
Kyte-Doolittle Hydrophobicity Value -0.209
Molecular Weight (kDa) 46331.8
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019855 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS1710b_A0589
Search term: bsaM

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592