Burkholderia pseudomallei 1710b, BURPS1710b_A0571 (bipB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 1710b
GCF_000012785.1|latest
Locus Tag
BURPS1710b_A0571
NCBI Locus TagBURPS1710B_RS21335
Name
bipB
Synonym: ipaB
Replicon chromosome II
Genomic location 765281 - 767143 (- strand)

Cross-References

RefSeq WP_004528817.1
GI 76818804
Entrez 3692329
GI 76818804
INSDC ABA52751.1
NCBI Locus Tag BURPS1710B_RS21335
NCBI Old Locus Tag BURPS1710b_A0571
RefSeq WP_004528817.1
UniParc UPI00005C38B1
UniProtKB Acc Q3JL23
UniProtKB ID BIPB_BURP1
UniRef100 UniRef100_Q3JL23
UniRef50 UniRef50_Q2T711
UniRef90 UniRef90_Q2T711

Product

Feature Type CDS
Coding Frame 1
Product Name
BipB protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.89
Kyte-Doolittle Hydrophobicity Value -0.084
Molecular Weight (kDa) 64646.1
Isoelectric Point (pI) 6.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 15 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019834 (323 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS1710b_A0571
Search term: bipB
Search term: BipB protein

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
The type III secretion system needle tip complex mediates host cell sensing and translocon insertion.
Veenendaal AK, Hodgkinson JL, Schwarzer L, Stabat D, Zenk SF, Blocker AJ
Mol Microbiol 2007 Mar;63(6):1719-30
PubMed ID: 17367391