Burkholderia pseudomallei 668, BURPS668_A2187 (bprP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_A2187
NCBI Locus TagBURPS668_RS26010
Name
bprP
Replicon chromosome II
Genomic location 2120620 - 2121591 (+ strand)

Cross-References

RefSeq WP_004188818.1
GI 126442553
Entrez 4886674
GI 126442553
INSDC ABN85549.1
NCBI Locus Tag BURPS668_RS26010
NCBI Old Locus Tag BURPS668_A2187
RefSeq WP_004188818.1
UniParc UPI00005C38BD
UniProtKB Acc A3NLG0
UniProtKB ID A3NLG0_BURP6
UniRef100 UniRef100_D7SFB6
UniRef50 UniRef50_D7SFB6
UniRef90 UniRef90_D7SFB6

Product

Feature Type CDS
Coding Frame 1
Product Name
putative transcriptional regulator
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 0.35
Kyte-Doolittle Hydrophobicity Value -0.147
Molecular Weight (kDa) 34684.8
Isoelectric Point (pI) 7.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 11 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019868 (325 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_A2187
Search term: bprP

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592