Burkholderia pseudomallei 668, BURPS668_A2152 (bicP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_A2152
NCBI Locus TagBURPS668_RS25850
Name
bicP
Synonym: sicP
Replicon chromosome II
Genomic location 2088881 - 2089336 (- strand)

Cross-References

RefSeq WP_011853451.1
GI 126445157
Entrez 4886402
GI 126445157
NCBI Locus Tag BURPS668_RS25850
NCBI Old Locus Tag BURPS668_A2152
RefSeq WP_011853451.1
UniProtKB Acc A3NLC5
UniProtKB ID A3NLC5_BURP6

Product

Feature Type CDS
Coding Frame 1
Product Name
Chaperone protein BicP
Product Name Confidence: Class 2
Synonyms type III secretion chaperone BicP
Evidence for Translation
Charge (pH 7) -13.10
Kyte-Doolittle Hydrophobicity Value 0.025
Molecular Weight (kDa) 16336.2
Isoelectric Point (pI) 4.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 4 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019822 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_A2152
Search term: bicP

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
Regulation of chaperone/effector complex synthesis in a bacterial type III secretion system.
Button JE, Galán JE
Mol Microbiol 2011 Sep;81(6):1474-83
PubMed ID: 21801239