Burkholderia multivorans ATCC 17616, Bmul_4613 (bceM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
GCF_000018505.1|latest
Locus Tag
Bmul_4613
NCBI Locus TagBMUL_RS23335
Name
bceM
Replicon chromosome 2
Genomic location 1716989 - 1717963 (+ strand)
CommentMember of the bce-II gene cluster

Cross-References

RefSeq WP_012217291.1
GI 161521156
Entrez 5768219
GI 161521156
NCBI Locus Tag BMUL_RS23335
NCBI Old Locus Tag Bmul_4613
RefSeq WP_012217291.1
UniProtKB Acc A9AM98
UniProtKB ID A9AM98_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
GDP-6-deoxy-D-lyxo-4-hexulose reductase BceM
Synonyms NAD-dependent epimerase/dehydratase
Evidence for Translation
Charge (pH 7) -0.65
Kyte-Doolittle Hydrophobicity Value -0.071
Molecular Weight (kDa) 34887.1
Isoelectric Point (pI) 6.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 635 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000738 (646 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_4613
Search term: bceM

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863