Burkholderia multivorans ATCC 17616, Bmul_4609 (bceQ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
GCF_000018505.1|latest
Locus Tag
Bmul_4609
NCBI Locus TagBMUL_RS23315
Name
bceQ
Replicon chromosome 2
Genomic location 1710664 - 1712130 (- strand)
CommentMember of the bce-II gene cluster
CommentDisruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis

Cross-References

RefSeq WP_006399606.1
GI 161521152
Entrez 5769011
GI 161521152
NCBI Locus Tag BMUL_RS23315
NCBI Old Locus Tag Bmul_4609
RefSeq WP_006399606.1
UniProtKB Acc A9AM94
UniProtKB ID A9AM94_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
polysaccharide biosynthesis protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 15.63
Kyte-Doolittle Hydrophobicity Value 0.838
Molecular Weight (kDa) 52206.4
Isoelectric Point (pI) 10.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 62 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003105 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_4609
Search term: bceQ

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863