Burkholderia multivorans ATCC 17616, Bmul_4604 (bceU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
GCF_000018505.1|latest
Locus Tag
Bmul_4604
NCBI Locus TagBMUL_RS23295
Name
bceU
Replicon chromosome 2
Genomic location 1703900 - 1705018 (+ strand)
CommentSince bceU is found in the genome sequences of all Bcc strains as well as in B. thailandensis, B. oklahomensis, and B. pseudomallei strains, the authors of PMID:19948863 considered it to belong as part of bce-II gene cluster.
CommentMember of the bce-II gene cluster

Cross-References

RefSeq WP_012217285.1
GI 161521147
Entrez 5768612
GI 161521147
NCBI Locus Tag BMUL_RS23295
NCBI Old Locus Tag Bmul_4604
RefSeq WP_012217285.1
UniProtKB Acc A9AM13
UniProtKB ID A9AM13_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
acyltransferase BceU
Product Name Confidence: Class 2
Synonyms acyltransferase
Evidence for Translation
Charge (pH 7) 17.46
Kyte-Doolittle Hydrophobicity Value 0.777
Molecular Weight (kDa) 40460.6
Isoelectric Point (pI) 10.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 239 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003110 (627 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_4604
Search term: bceU

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863