Burkholderia multivorans ATCC 17616, Bmul_2557 (ldhR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
GCF_000018505.1|latest
Locus Tag
Bmul_2557
NCBI Locus TagBMUL_RS12980
Name
ldhR
Replicon chromosome 1
Genomic location 2783676 - 2784659 (+ strand)

Cross-References

RefSeq WP_012214022.1
GI 161525726
Entrez 5766275
GI 161525726
NCBI Locus Tag BMUL_RS12980
NCBI Old Locus Tag Bmul_2557
RefSeq WP_012214022.1
UniProtKB Acc A9AFM0
UniProtKB ID A9AFM0_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
LdhR
Product Name Confidence: Class 1
Synonyms LysR family transcriptional regulator
Evidence for Translation
Charge (pH 7) 2.41
Kyte-Doolittle Hydrophobicity Value -0.054
Molecular Weight (kDa) 35606.2
Isoelectric Point (pI) 7.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000688 (636 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_2557
Search term: ldhR
Search term: LdhR

Human Homologs

References

Regulator LdhR and d-Lactate Dehydrogenase LdhA of Burkholderia multivorans Play Roles in Carbon Overflow and in Planktonic Cellular Aggregate Formation.
Silva IN, Ramires MJ, Azevedo LA, Guerreiro AR, Tavares AC, Becker JD, Moreira LM
Appl Environ Microbiol 2017 Oct 1;83(19)
PubMed ID: 28733286