Burkholderia multivorans ATCC 17616, Bmul_1072 (hemP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
GCF_000018505.1|latest
Locus Tag
Bmul_1072
NCBI Locus TagBMUL_RS05450
Name
hemP
Replicon chromosome 1
Genomic location 1172477 - 1172722 (- strand)

Cross-References

RefSeq WP_006402044.1
GI 161524248
Entrez 5765945
GI 161524248
NCBI Locus Tag BMUL_RS05450
NCBI Old Locus Tag Bmul_1072
RefSeq WP_006402044.1
UniProtKB Acc A9AG31
UniProtKB ID A9AG31_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
Hemin uptake protein HemP
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 8.70
Kyte-Doolittle Hydrophobicity Value -0.464
Molecular Weight (kDa) 8541.6
Isoelectric Point (pI) 12.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 22 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002093 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_1072
Search term: hemP

Human Homologs

References

The Small Protein HemP Is a Transcriptional Activator for the Hemin Uptake Operon in Burkholderia multivorans ATCC 17616.
Sato T, Nonoyama S, Kimura A, Nagata Y, Ohtsubo Y, Tsuda M
Appl Environ Microbiol 2017 Aug 15;83(16)
PubMed ID: 28625994