Burkholderia mallei ATCC 23344, BMAA1547 (bsaM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1547
Name
bsaM
Synonym: sctD
Replicon chromosome 2
Genomic location 1676120 - 1677406 (+ strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106135.1
GI 53716323
NCBI Locus Tag BMAA1547
RefSeq YP_106135.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system inner membrane ring component BsaM (T3SS-3)
Product Name Confidence: Class 2
Synonyms type III secretion system protein BsaM
Evidence for Translation
Charge (pH 7) -3.90
Kyte-Doolittle Hydrophobicity Value -0.207
Molecular Weight (kDa) 46321.8
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019855 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1547
Search term: bsaM

Human Homologs

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
PubMed ID: 24884837
Structural insights into the assembly of the type III secretion needle complex.
Marlovits TC, Kubori T, Sukhan A, Thomas DR, Galán JE, Unger VM
Science 2004 Nov 5;306(5698):1040-2
PubMed ID: 15528446
Molecular characterization and assembly of the needle complex of the Salmonella typhimurium type III protein secretion system.
Kubori T, Sukhan A, Aizawa SI, Galán JE
Proc Natl Acad Sci U S A 2000 Aug 29;97(18):10225-30
PubMed ID: 10944190