Burkholderia mallei ATCC 23344, BMAA1540 (bsaS)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia mallei ATCC 23344
GCF_000011705.1|latest |
| Locus Tag |
BMAA1540
|
| Name |
bsaS
|
| Replicon | chromosome 2 |
| Genomic location | 1668125 - 1669435 (- strand) |
| Comment | This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus. |
Cross-References
| RefSeq | YP_106129.1 |
| GI | 53716453 |
| NCBI Locus Tag | BMAA1540 |
| RefSeq | YP_106129.1,GeneID |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
type III secretion system ATPase BsaS (T3SS-3)
|
| Synonyms |
ATP synthase SpaL |
| Evidence for Translation | |
| Charge (pH 7) | -2.68 |
| Kyte-Doolittle Hydrophobicity Value | -0.099 |
| Molecular Weight (kDa) | 46897.7 |
| Isoelectric Point (pI) | 6.28 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Virulence Evidence
| Source 1 | |
| Database | VFDB : VF0428 |
| Category | T3SS-3 |
| Evidence |
ECO:0000250
sequence similarity evidence used in manual assertion
|
| Host Organism | |
| Notes | |
| Annotation transferred from | Burkholderia pseudomallei K96243 |
| Reference | 17984080 |
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG019845 (322 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BMAA1540
Search term: bsaS
Search term: type III secretion system ATPase BsaS (T3SS-3)
|
Human Homologs
References
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|
|
Burkholderia pseudomallei type III secretion system cluster 3 ATPase BsaS, a chemotherapeutic target for small-molecule ATPase inhibitors.
Gong L, Lai SC, Treerat P, Prescott M, Adler B, Boyce JD, Devenish RJ
Infect Immun 2015 Apr;83(4):1276-85
PubMed ID: 25605762
|
|
Identification of a regulatory cascade controlling Type III Secretion System 3 gene expression in Burkholderia pseudomallei.
Sun GW, Chen Y, Liu Y, Tan GY, Ong C, Tan P, Gan YH
Mol Microbiol 2010 May;76(3):677-89
PubMed ID: 20345664
|