Burkholderia mallei ATCC 23344, BMAA1538 (bsaU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1538
Name
bsaU
Synonym: sctP
Replicon chromosome 2
Genomic location 1666439 - 1667686 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106128.1
GI 53716454
NCBI Locus Tag BMAA1538
RefSeq YP_106128.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
needle length control protein BsaU (T3SS-3)
Product Name Confidence: Class 2
Synonyms BsaU protein
Evidence for Translation
Charge (pH 7) 6.06
Kyte-Doolittle Hydrophobicity Value -0.656
Molecular Weight (kDa) 42280.5
Isoelectric Point (pI) 9.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019843 (305 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1538
Search term: bsaU

Human Homologs

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
Molecular characterization and assembly of the needle complex of the Salmonella typhimurium type III protein secretion system.
Kubori T, Sukhan A, Aizawa SI, Galán JE
Proc Natl Acad Sci U S A 2000 Aug 29;97(18):10225-30
PubMed ID: 10944190
Identification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence.
Pilatz S, Breitbach K, Hein N, Fehlhaber B, Schulze J, Brenneke B, Eberl L, Steinmetz I
Infect Immun 2006 Jun;74(6):3576-86
PubMed ID: 16714590