Burkholderia mallei ATCC 23344, BMAA1533 (bsaZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1533
Name
bsaZ
Synonym: sctU
Replicon chromosome 2
Genomic location 1662471 - 1663706 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106123.1
GI 53716465
NCBI Locus Tag BMAA1533
RefSeq YP_106123.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system export apparatus protein BsaZ (T3SS-3)
Product Name Confidence: Class 2
Synonyms surface presentation of antigens protein SpaS
Evidence for Translation
Charge (pH 7) 5.05
Kyte-Doolittle Hydrophobicity Value 0.084
Molecular Weight (kDa) 44493.8
Isoelectric Point (pI) 8.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
T3SS
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019837 (326 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1533
Search term: bsaZ

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
Burkholderia pseudomallei type III secretion system mutants exhibit delayed vacuolar escape phenotypes in RAW 264.7 murine macrophages.
Burtnick MN, Brett PJ, Nair V, Warawa JM, Woods DE, Gherardini FC
Infect Immun 2008 Jul;76(7):2991-3000
PubMed ID: 18443088
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268
An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen.
Stevens MP, Wood MW, Taylor LA, Monaghan P, Hawes P, Jones PW, Wallis TS, Galyov EE
Mol Microbiol 2002 Nov;46(3):649-59
PubMed ID: 12410823