Burkholderia mallei ATCC 23344, BMAA1530 (bipC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1530
Name
bipC
Synonym: sctB
Replicon chromosome 2
Genomic location 1658648 - 1659907 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106120.1
GI 53716468
NCBI Locus Tag BMAA1530
RefSeq YP_106120.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
translocator protein BipC (T3SS-3)
Product Name Confidence: Class 2
Synonyms type III secretion target BipC
Evidence for Translation
Charge (pH 7) 4.63
Kyte-Doolittle Hydrophobicity Value -0.583
Molecular Weight (kDa) 44322.2
Isoelectric Point (pI) 8.97

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Unknown (This protein may have multiple localization sites) Class 3
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019833 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1530
Search term: bipC

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
Eukaryotic pathways targeted by the type III secretion system effector protein, BipC, involved in the intracellular lifecycle of Burkholderia pseudomallei.
Kang WT, Vellasamy KM, Vadivelu J
Sci Rep 2016 Sep 16;6:33528
PubMed ID: 27634329
<i>Burkholderia pseudomallei</i> type III secreted protein BipC: role in actin modulation and translocation activities required for the bacterial intracellular lifecycle.
Kang WT, Vellasamy KM, Rajamani L, Beuerman RW, Vadivelu J
PeerJ 2016;4:e2532
PubMed ID: 28028452