Burkholderia mallei SAVP1, BMASAVP1_0599 (bimA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei SAVP1
GCF_000015465.1|latest
Locus Tag
BMASAVP1_0599
NCBI Locus TagBMASAVP1_RS02420
Name
bimA
Replicon chromosome II
Genomic location 605940 - 606518 (+ strand)

Cross-References

RefSeq YP_990207.1
GI 121596482
Entrez 4676966
GI 121596482
INSDC ABM47811.1
NCBI Locus Tag BMASAVP1_RS02420
NCBI Old Locus Tag BMASAVP1_0599
RefSeq WP_004266230.1
UniParc UPI0000ED136E
UniProtKB Acc A1UW54
UniProtKB ID A1UW54_BURMS
UniRef100 UniRef100_A2RXV6
UniRef50 UniRef50_A3MF13
UniRef90 UniRef90_A3MF13

Product

Feature Type CDS
Coding Frame 1
Product Name
Burkholderia intracellular motility A, BimA
Product Name Confidence: Class 2
Synonyms intracellular motility protein A
Evidence for Translation
Charge (pH 7) 3.19
Kyte-Doolittle Hydrophobicity Value -0.163
Molecular Weight (kDa) 19537.5
Isoelectric Point (pI) 9.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0427
Category Burkholderia intracellular motility A
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 62 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019364 (221 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMASAVP1_0599
Search term: bimA

Human Homologs

References

Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei.
Stevens MP, Stevens JM, Jeng RL, Taylor LA, Wood MW, Hawes P, Monaghan P, Welch MD, Galyov EE
Mol Microbiol 2005 Apr;56(1):40-53
PubMed ID: 15773977