Burkholderia dolosa AU0158, AK34_RS07150 (bceA)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia dolosa AU0158 (complete genome)
Locus Tag
NCBI Old Locus TagAK34_4592
Synonym: cpsB
Replicon chromosome 2
Genomic location 1672141 - 1673667 (+ strand)
CommentMember of the bce-I gene cluster


RefSeq WP_035973610.1
GI 738012229
NCBI Locus Tag AK34_RS07150
NCBI Old Locus Tag AK34_4592
RefSeq WP_035973610.1


Feature Type CDS
Coding Frame 1
Product Name
Product Name Confidence: Class 2
Synonyms mannose-1-phosphate guanyltransferase
Evidence for Translation
Charge (pH 7) -8.59
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 55029.9
Isoelectric Point (pI) 6.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003312 (1226 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: AK34_RS07150
Search term: bceA
Search term: BceA

Human Homologs


Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
The Burkholderia cepacia bceA gene encodes a protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Wopperer J, Eberl L, Sá-Correia I, Leitão JH
Biochem Biophys Res Commun 2007 Feb 2;353(1):200-6
PubMed ID: 17184737
Functional analysis of the Burkholderia cenocepacia J2315 BceAJ protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Leitão JH
Appl Microbiol Biotechnol 2008 Oct;80(6):1015-22
PubMed ID: 18668237