Burkholderia mallei NCTC 10247, BMA10247_A0749 (bsaX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10247
GCF_000015625.1|latest
Locus Tag
BMA10247_A0749
NCBI Locus TagBMA10247_RS03070
Name
bsaX
Replicon chromosome II
Genomic location 693370 - 693624 (+ strand)

Cross-References

RefSeq WP_004187417.1
GI 126446907
Entrez 4890749
GI 126446907
INSDC ABO02873.1
NCBI Locus Tag BMA10247_RS03070
NCBI Old Locus Tag BMA10247_A0749
RefSeq WP_004187417.1
UniParc UPI000043BD22
UniProtKB Acc A3MCG4
UniProtKB ID A3MCG4_BURM7
UniRef100 UniRef100_A0A069BAC3
UniRef50 UniRef50_A1JQ91
UniRef90 UniRef90_A0A069BAC3

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein BsaX
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -0.08
Kyte-Doolittle Hydrophobicity Value 1.206
Molecular Weight (kDa) 8861.7
Isoelectric Point (pI) 6.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 140 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019839 (327 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10247_A0749
Search term: bsaX

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592