Burkholderia mallei NCTC 10247, BMA10247_A0747 (bsaV)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10247
GCF_000015625.1|latest
Locus Tag
BMA10247_A0747
NCBI Locus TagBMA10247_RS03060
Name
bsaV
Replicon chromosome II
Genomic location 691657 - 692664 (+ strand)

Cross-References

RefSeq WP_004203138.1
GI 126447935
Entrez 4891045
GI 126447935
INSDC ABO03901.1
NCBI Locus Tag BMA10247_RS03060
NCBI Old Locus Tag BMA10247_A0747
RefSeq WP_004203138.1
UniParc UPI0000558666
UniProtKB Acc A3MCG2
UniProtKB ID A3MCG2_BURM7
UniRef100 UniRef100_A3MCG2
UniRef50 UniRef50_Q2T717
UniRef90 UniRef90_Q62B01

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein BsaV
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.32
Kyte-Doolittle Hydrophobicity Value -0.039
Molecular Weight (kDa) 36198.9
Isoelectric Point (pI) 6.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 14 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019841 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10247_A0747
Search term: bsaV

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592