Burkholderia mallei NCTC 10247, BMA10247_A0735 (bsaL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10247
GCF_000015625.1|latest
Locus Tag
BMA10247_A0735
NCBI Locus TagBMA10247_RS03010
Name
bsaL
Replicon chromosome II
Genomic location 680427 - 680696 (- strand)

Cross-References

RefSeq WP_004187639.1
GI 126445643
Entrez 4889116
GI 126445643
INSDC ABO01609.1
NCBI Locus Tag BMA10247_RS03010
NCBI Old Locus Tag BMA10247_A0735
RefSeq WP_004187639.1
UniParc UPI0000441485
UniProtKB Acc A3MCF0
UniProtKB ID A3MCF0_BURM7
UniRef100 UniRef100_A0A095M298
UniRef50 UniRef50_Q2T727
UniRef90 UniRef90_Q2T727

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein BsaL
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.02
Kyte-Doolittle Hydrophobicity Value -0.620
Molecular Weight (kDa) 9923.9
Isoelectric Point (pI) 4.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2G0U UNKNOWN FUNCTION 02/13/06 Solution Structure of Monomeric BsaL, the Type III Secretion Needle Protein of Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI NOT SOLUTION NMR 98.8

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 12 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019858 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10247_A0735
Search term: bsaL

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592