Burkholderia mallei NCTC 10229, BMA10229_2087 (bprD)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia mallei NCTC 10229
GCF_000015605.1|latest |
| Locus Tag |
BMA10229_2087
|
| NCBI Locus Tag | BMA10229_RS09045 |
| Name |
bprD
|
| Replicon | chromosome II |
| Genomic location | 2137544 - 2137987 (+ strand) |
Cross-References
| RefSeq | WP_004203128.1 |
| GI | 124382863 |
| Entrez | 4790404 |
| GI | 124382863 |
| INSDC | ABN00465.2 |
| NCBI Locus Tag | BMA10229_RS09045 |
| NCBI Old Locus Tag | BMA10229_2087 |
| RefSeq | WP_004203128.1 |
| UniParc | UPI000043BD13 |
| UniProtKB Acc | A2S1R2 |
| UniProtKB Acc | A2S1R3 |
| UniProtKB ID | A2S1R2_BURM9 |
| UniProtKB ID | A2S1R2_BURM9 |
| UniRef100 | UniRef100_A0A097XM68 |
| UniRef50 | UniRef50_Q2T700 |
| UniRef90 | UniRef90_Q2T700 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
hypothetical protein
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 16.92 |
| Kyte-Doolittle Hydrophobicity Value | -0.686 |
| Molecular Weight (kDa) | 16672.2 |
| Isoelectric Point (pI) | 11.42 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
| Look for predicted 3D structure in AlphaFold DB: Search |
| Look for predicted 3D structure in AlphaFold DB: Search |
Virulence Evidence
| Source 1 | |
| Database | VFDB : VF0428 |
| Category | T3SS-3 |
| Evidence |
ECO:0000250
sequence similarity evidence used in manual assertion
|
| Host Organism | |
| Notes | |
| Annotation transferred from | Burkholderia pseudomallei K96243 |
| Reference | 17984080 |
Pathogen Association Analysis
| Results |
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in one genus
|
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG019819 (316 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BMA10229_2087
Search term: bprD
|
Human Homologs
References
|
Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
|