Burkholderia mallei NCTC 10229, BMA10229_2084 (bicP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10229
GCF_000015605.1|latest
Locus Tag
BMA10229_2084
NCBI Locus TagBMA10229_RS09035
Name
bicP
Synonym: sicP
Replicon chromosome II
Genomic location 2135918 - 2136373 (+ strand)

Cross-References

RefSeq WP_004187648.1
GI 124381179
Entrez 4789491
GI 124381179
INSDC ABM99415.2
NCBI Locus Tag BMA10229_RS09035
NCBI Old Locus Tag BMA10229_2084
RefSeq WP_004187648.1
UniParc UPI000043BD15
UniProtKB Acc A2S1R0
UniProtKB ID A2S1R0_BURM9
UniRef100 UniRef100_A0A095QSH1
UniRef50 UniRef50_Q2T702
UniRef90 UniRef90_Q2T702

Product

Feature Type CDS
Coding Frame 1
Product Name
Chaperone protein BicP
Product Name Confidence: Class 2
Synonyms type III secretion chaperone BicP
Evidence for Translation
Charge (pH 7) -13.10
Kyte-Doolittle Hydrophobicity Value 0.009
Molecular Weight (kDa) 16308.1
Isoelectric Point (pI) 4.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 4 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019822 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10229_2084
Search term: bicP

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
Regulation of chaperone/effector complex synthesis in a bacterial type III secretion system.
Button JE, Galán JE
Mol Microbiol 2011 Sep;81(6):1474-83
PubMed ID: 21801239