Burkholderia mallei NCTC 10229, BMA10229_2060 (bsaO)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10229
GCF_000015605.1|latest
Locus Tag
BMA10229_2060
NCBI Locus TagBMA10229_RS08920
Name
bsaO
Replicon chromosome II
Genomic location 2110937 - 2112814 (+ strand)

Cross-References

RefSeq WP_004187426.1
GI 124382842
Entrez 4788470
GI 124382842
NCBI Locus Tag BMA10229_RS08920
NCBI Old Locus Tag BMA10229_2060
RefSeq WP_004187426.1
UniProtKB Acc A2S1N7
UniProtKB ID A2S1N7_BURM9

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein BsaO
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.57
Kyte-Doolittle Hydrophobicity Value -0.145
Molecular Weight (kDa) 66569.4
Isoelectric Point (pI) 6.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019850 (324 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10229_2060
Search term: bsaO

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592