Burkholderia mallei NCTC 10229, BMA10229_2048 (bprQ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10229
GCF_000015605.1|latest
Locus Tag
BMA10229_2048
NCBI Locus TagBMA10229_RS08870
Name
bprQ
Replicon chromosome II
Genomic location 2103148 - 2103585 (- strand)

Cross-References

RefSeq WP_004198142.1
GI 124381595
Entrez 4789034
GI 124381595
INSDC ABM99083.2
NCBI Locus Tag BMA10229_RS08870
NCBI Old Locus Tag BMA10229_2048
RefSeq WP_004198142.1
UniParc UPI0000558660
UniProtKB Acc A2S1M3
UniProtKB Acc A2S1M3
UniProtKB ID A2S1M3_BURM9
UniProtKB ID A2S1M5_BURM9
UniRef100 UniRef100_A0A095U5X5
UniRef50 UniRef50_D7SFB7
UniRef90 UniRef90_D7SFB7

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 1.07
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 16030.1
Isoelectric Point (pI) 7.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search
Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019869 (314 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10229_2048
Search term: bprQ

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592