Burkholderia mallei NCTC 10229, BMA10229_0813 (boaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10229
GCF_000015605.1|latest
Locus Tag
BMA10229_0813
Name
boaA
Replicon chromosome II
Genomic location 853983 - 856130 (- strand)

Cross-References

RefSeq YP_001024628.1
GI 124382050
Entrez 4789623
GI 124382050
RefSeq YP_001024628.1
UniProtKB Acc A2RY59
UniProtKB ID A2RY59_BURM9

Product

Feature Type CDS
Coding Frame 1
Product Name
Burkholderia oligomeric coiled-coil adhesin A, BoaA
Product Name Confidence: Class 2
Synonyms haemagluttinin motif-containing protein
Evidence for Translation
Charge (pH 7) -5.05
Kyte-Doolittle Hydrophobicity Value 0.205
Molecular Weight (kDa) 65910.2
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0434
Category Burkholderia oligomeric coiled-coil adhesin A
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 71 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG015417 (395 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10229_0813
Search term: boaA

Human Homologs

References

Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells.
Balder R, Lipski S, Lazarus JJ, Grose W, Wooten RM, Hogan RJ, Woods DE, Lafontaine ER
BMC Microbiol 2010 Sep 28;10:250
PubMed ID: 20920184