Burkholderia cenocepacia MC0-3, Bcenmc03_5824 (ecfH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_5824
Name
ecfH
Replicon chromosome 2
Genomic location 3003986 - 3004780 (+ strand)

Cross-References

RefSeq YP_001779435.1
GI 170738175
Entrez 6128628
GI 170738175
RefSeq YP_001779435.1
UniProtKB Acc B1K457
UniProtKB ID B1K457_BURCC

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase sigma factor
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfH
Evidence for Translation
Charge (pH 7) -5.35
Kyte-Doolittle Hydrophobicity Value -0.826
Molecular Weight (kDa) 29703.8
Isoelectric Point (pI) 5.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 473 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003549 (228 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_5824
Search term: ecfH

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948