Burkholderia cenocepacia MC0-3, Bcenmc03_5577 (mgtC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_5577
NCBI Locus TagBCENMC03_RS27915
Name
mgtC
Replicon chromosome 2
Genomic location 2719778 - 2720485 (- strand)

Cross-References

RefSeq WP_006483946.1
GI 170737932
Entrez 6128385
GI 170737932
INSDC ACA94702.1
NCBI Locus Tag BCENMC03_RS27915
NCBI Old Locus Tag Bcenmc03_5577
RefSeq WP_006483946.1
UniParc UPI000052DD8C
UniProtKB Acc B1K9T7
UniProtKB ID B1K9T7_BURCC
UniRef100 UniRef100_A0A071M8X9
UniRef50 UniRef50_G8MNW9
UniRef90 UniRef90_A0A087NXB9

Product

Feature Type CDS
Coding Frame 1
Product Name
MgtC/SapB transporter
Synonyms
Evidence for Translation
Charge (pH 7) 2.59
Kyte-Doolittle Hydrophobicity Value 0.347
Molecular Weight (kDa) 24803.6
Isoelectric Point (pI) 8.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 317 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003717 (642 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_5577
Search term: mgtC

Human Homologs

References

The mgtC gene of Burkholderia cenocepacia is required for growth under magnesium limitation conditions and intracellular survival in macrophages.
Maloney KE, Valvano MA
Infect Immun 2006 Oct;74(10):5477-86
PubMed ID: 16988222