Burkholderia cenocepacia MC0-3, Bcenmc03_5576 (cepR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_5576
NCBI Locus TagBCENMC03_RS27910
Name
cepR
Replicon chromosome 2
Genomic location 2719003 - 2719722 (+ strand)

Cross-References

RefSeq WP_011547409.1
GI 170737931
Entrez 6128384
GI 170737931
INSDC ACA94701.1
NCBI Locus Tag BCENMC03_RS27910
NCBI Old Locus Tag Bcenmc03_5576
RefSeq WP_011547409.1
UniParc UPI000052E790
UniProtKB Acc B1K9T6
UniProtKB ID B1K9T6_BURCC
UniRef100 UniRef100_B1K9T6
UniRef50 UniRef50_P58590
UniRef90 UniRef90_B4EMD0

Product

Feature Type CDS
Coding Frame 1
Product Name
LuxR family transcriptional regulator
Product Name Confidence: Class 1
Synonyms transcriptional regulator CepR
Evidence for Translation
Charge (pH 7) -2.20
Kyte-Doolittle Hydrophobicity Value -0.053
Molecular Weight (kDa) 26608.2
Isoelectric Point (pI) 6.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0433
Category Quorum sensing system
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 367 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003718 (1367 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_5576
Search term: cepR

Human Homologs

References

Distribution of quorum-sensing genes in the Burkholderia cepacia complex.
Lutter E, Lewenza S, Dennis JJ, Visser MB, Sokol PA
Infect Immun 2001 Jul;69(7):4661-6
PubMed ID: 11402012