Burkholderia cenocepacia MC0-3, Bcenmc03_4628 (ecfK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_4628
NCBI Locus TagBCENMC03_RS23290
Name
ecfK
Replicon chromosome 2
Genomic location 1621840 - 1622727 (- strand)

Cross-References

RefSeq WP_012339136.1
GI 170736996
Entrez 6127448
GI 170736996
NCBI Locus Tag BCENMC03_RS23290
NCBI Old Locus Tag Bcenmc03_4628
RefSeq WP_012339136.1
UniProtKB Acc B1K2V6
UniProtKB ID B1K2V6_BURCC

Product

Feature Type CDS
Coding Frame 1
Product Name
ECF subfamily RNA polymerase sigma-24 factor
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfK
Evidence for Translation
Charge (pH 7) -0.92
Kyte-Doolittle Hydrophobicity Value -0.282
Molecular Weight (kDa) 33201.5
Isoelectric Point (pI) 6.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 208 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000010 (703 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_4628
Search term: ecfK

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948