Burkholderia cenocepacia MC0-3, Bcenmc03_4148 (atsR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_4148
NCBI Locus TagBCENMC03_RS20925
Name
atsR
Replicon chromosome 2
Genomic location 1087987 - 1089819 (+ strand)

Cross-References

RefSeq WP_011548429.1
GI 170736529
Entrez 6126981
GI 170736529
NCBI Locus Tag BCENMC03_RS20925
NCBI Old Locus Tag Bcenmc03_4148
RefSeq WP_011548429.1
UniProtKB Acc B1K780
UniProtKB ID B1K780_BURCC

Product

Feature Type CDS
Coding Frame 1
Product Name
histidine kinase
Product Name Confidence: Class 1
Synonyms adherence and T6 secretion system regulator AtsR
Evidence for Translation
Charge (pH 7) 2.05
Kyte-Doolittle Hydrophobicity Value -0.015
Molecular Weight (kDa) 67617.2
Isoelectric Point (pI) 7.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 620 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004546 (629 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_4148
Search term: atsR
Search term: histidine kinase

Human Homologs

References

A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384