Burkholderia cenocepacia MC0-3, Bcenmc03_3702 (bceD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_3702
NCBI Locus TagBCENMC03_RS18725
Name
bceD
Replicon chromosome 2
Genomic location 607488 - 607931 (- strand)

Cross-References

RefSeq WP_011548197.1
GI 170736084
Entrez 6126536
GI 170736084
INSDC ACA92854.1
NCBI Locus Tag BCENMC03_RS18725
NCBI Old Locus Tag Bcenmc03_3702
RefSeq WP_011548197.1
UniParc UPI0000D7EC21
UniProtKB Acc B1K4D6
UniProtKB ID B1K4D6_BURCC
UniRef100 UniRef100_B1K4D6
UniRef50 UniRef50_Q2T7V4
UniRef90 UniRef90_A0A095E814

Product

Feature Type CDS
Coding Frame 1
Product Name
protein tyrosine phosphatase
Product Name Confidence: Class 1
Synonyms phosphotyrosine phosphatase BceD
Evidence for Translation
Charge (pH 7) 4.58
Kyte-Doolittle Hydrophobicity Value -0.346
Molecular Weight (kDa) 16373.6
Isoelectric Point (pI) 8.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 292 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004849 (632 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_3702
Search term: bceD

Human Homologs

References

Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Ferreira AS, Leitão JH, Sousa SA, Cosme AM, Sá-Correia I, Moreira LM
Appl Environ Microbiol 2007 Jan;73(2):524-34
PubMed ID: 17114319