Burkholderia cenocepacia MC0-3, Bcenmc03_2826 (sigM)

Gene Feature Overview

Strain	Burkholderia cenocepacia MC0-3 GCF_000019505.1|latest
Locus Tag	Bcenmc03_2826
NCBI Locus Tag	BCENMC03_RS14320
Name	sigM
Replicon	chromosome 1
Genomic location	3145470 - 3146405 (+ strand)

Cross-References

RefSeq	WP_006477765.1
GI	170734160
Entrez	6124488
GI	170734160
INSDC	ACA91985.1
NCBI Locus Tag	BCENMC03_RS14320
NCBI Old Locus Tag	Bcenmc03_2826
RefSeq	WP_006477765.1
UniParc	UPI000052E36E
UniProtKB Acc	B1JYR2
UniProtKB ID	B1JYR2_BURCC
UniRef100	UniRef100_B1JYR2
UniRef50	UniRef50_P50511
UniRef90	UniRef90_Q9AMB8

Product

Feature Type	CDS
Coding Frame	1
Product Name	RNA polymerase factor sigma-32
Synonyms	sigma factor 70 SigM
Evidence for Translation
Charge (pH 7)	-3.82
Kyte-Doolittle Hydrophobicity Value	-0.329
Molecular Weight (kDa)	34568.9
Isoelectric Point (pI)	6.25

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002666 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: Bcenmc03_2826 Search term: sigM Search term: RNA polymerase factor sigma-32

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability. Menard A, de Los Santos PE, Graindorge A, Cournoyer B BMC Genomics 2007 Sep 4;8:308 PubMed ID: 17784948