Burkholderia xenovorans LB400, Bxe_A1420

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia xenovorans LB400 (Paraburkholderia)
GCF_000013645.1|latest
Locus Tag
Bxe_A1420
NCBI Locus TagBXE_RS14865
Name
Replicon chromosome 1
Genomic location 3349999 - 3351594 (+ strand)

Cross-References

RefSeq WP_011489106.1
GI 91784381
Entrez 4004406
GI 91784381
INSDC ABE31535.1
NCBI Locus Tag BXE_RS14865
NCBI Old Locus Tag Bxe_A1420
RefSeq WP_011489106.1,GeneID
UniParc UPI00003C3F03
UniProtKB Acc Q13WK4
UniProtKB ID Q13WK4_BURXL
UniRef100 UniRef100_Q13WK4
UniRef50 UniRef50_Q84HH8
UniRef90 UniRef90_Q13WK4

Product

Feature Type CDS
Coding Frame 1
Product Name
aldehyde dehydrogenase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.50
Kyte-Doolittle Hydrophobicity Value 0.139
Molecular Weight (kDa) 55495.3
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2Y51 OXIDOREDUCTASE 01/11/11 Crystal structure of E167A mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 BURKHOLDERIA XENOVORANS LB400 1.6 X-RAY DIFFRACTION 99.8
2Y5D OXIDOREDUCTASE 01/12/11 Crystal structure of C296A mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 BURKHOLDERIA XENOVORANS LB400 1.4 X-RAY DIFFRACTION 99.8
2Y53 OXIDOREDUCTASE 01/11/11 Crystal structure of E257Q mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 BURKHOLDERIA XENOVORANS LB400 1.4 X-RAY DIFFRACTION 99.8
2VRO OXIDOREDUCTASE 04/09/08 Crystal structure of aldehyde dehydrogenase from Burkholderia xenovorans LB400 BURKHOLDERIA XENOVORANS 1.6 X-RAY DIFFRACTION 100.0
2Y52 OXIDOREDUCTASE 01/11/11 Crystal structure of E496A mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 BURKHOLDERIA XENOVORANS LB400 1.65 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 560 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG027703 (11 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bxe_A1420

References

Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400.
Bains J, Boulanger MJ
J Mol Biol 2008 Jun 6;379(3):597-608
PubMed ID: 18462753