Burkholderia vietnamiensis G4, Bcep1808_5259 (mgtC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia vietnamiensis G4
GCF_000016205.1|latest
Locus Tag
Bcep1808_5259
NCBI Locus TagBCEP1808_RS26195
Name
mgtC
Replicon chromosome 2
Genomic location 2190831 - 2191538 (+ strand)

Cross-References

RefSeq WP_011882531.1
GI 134293937
Entrez 4951477
GI 134293937
INSDC ABO58208.1
NCBI Locus Tag BCEP1808_RS26195
NCBI Old Locus Tag Bcep1808_5259
RefSeq WP_011882531.1
UniParc UPI00003A64F5
UniProtKB Acc A4JPK5
UniProtKB ID A4JPK5_BURVG
UniRef100 UniRef100_A4JPK5
UniRef50 UniRef50_G8MNW9
UniRef90 UniRef90_A0A087NXB9

Product

Feature Type CDS
Coding Frame 1
Product Name
MgtC/SapB transporter
Synonyms
Evidence for Translation
Charge (pH 7) 3.59
Kyte-Doolittle Hydrophobicity Value 0.397
Molecular Weight (kDa) 24731.6
Isoelectric Point (pI) 8.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 317 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003717 (642 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcep1808_5259
Search term: mgtC

Human Homologs

References

The mgtC gene of Burkholderia cenocepacia is required for growth under magnesium limitation conditions and intracellular survival in macrophages.
Maloney KE, Valvano MA
Infect Immun 2006 Oct;74(10):5477-86
PubMed ID: 16988222