Burkholderia thailandensis E264 ATCC 700388, BTH_I2393 (fenI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_I2393
NCBI Locus TagBTH_RS24410
Name
fenI
Replicon chromosome I
Genomic location 2720796 - 2722451 (+ strand)
Transposon Mutants 3 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq YP_442914.1
GI 83720951
Entrez 3849476
GI 83720951
INSDC ABC38839.1
NCBI Locus Tag BTH_RS24410
NCBI Old Locus Tag BTH_I2393
RefSeq YP_442914.1
UniParc UPI00006684D1
UniProtKB Acc Q2SVY5
UniProtKB ID Q2SVY5_BURTA
UniRef100 UniRef100_Q2SVY5
UniRef50 UniRef50_A0A095QXY7
UniRef90 UniRef90_A0A096Z1L0

Product

Feature Type CDS
Coding Frame 1
Product Name
fenI protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.71
Kyte-Doolittle Hydrophobicity Value -0.459
Molecular Weight (kDa) 61443.0
Isoelectric Point (pI) 6.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 130 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019629 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_I2393
Search term: fenI
Search term: fenI protein

Human Homologs

References

Global Awakening of Cryptic Biosynthetic Gene Clusters in Burkholderia thailandensis.
Gupta A, Bedre R, Thapa SS, Sabrin A, Wang G, Dassanayake M, Grove A
ACS Chem Biol 2017 Dec 15;12(12):3012-3021
PubMed ID: 29087175