Burkholderia thailandensis E264 ATCC 700388, BTH_II1512 (btaI1)

Gene Feature Overview

Strain	Burkholderia thailandensis E264 ATCC 700388 GCF_000012365.1|latest
Locus Tag	BTH_II1512
NCBI Locus Tag	BTH_RS07735
Name	btaI1
Replicon	chromosome II
Genomic location	1780524 - 1781135 (+ strand)
Transposon Mutants	4 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq	YP_439708.1
GI	83717635
Entrez	3844796
GI	83717635
INSDC	AIP28784.1
NCBI Locus Tag	BTH_RS07735
NCBI Old Locus Tag	BTH_II1512
RefSeq	WP_009900398.1
UniParc	UPI000034EBB6
UniProtKB Acc	Q2T541
UniProtKB ID	Q2T541_BURTA
UniRef100	UniRef100_Q2T541
UniRef50	UniRef50_O30920
UniRef90	UniRef90_Q8KRT8

Product

Feature Type	CDS
Coding Frame	1
Product Name	BtaI1
Synonyms	N-acyl homoserine lactone synthase
Evidence for Translation
Charge (pH 7)	-4.95
Kyte-Doolittle Hydrophobicity Value	0.013
Molecular Weight (kDa)	22221.2
Isoelectric Point (pI)	5.28

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database	VFDB : VF0433
Category	Quorum sensing system
Evidence	ECO:0000250 sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from	Burkholderia pseudomallei K96243
Reference	17984080

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 63 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003720 (981 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BTH_II1512 Search term: btaI1 Search term: BtaI1

Human Homologs

References

Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation. Chandler JR, Duerkop BA, Hinz A, West TE, Herman JP, Churchill ME, Skerrett SJ, Greenberg EP J Bacteriol 2009 Oct;191(19):5901-9 PubMed ID: 19648250