Burkholderia thailandensis E264 ATCC 700388, BTH_II1275

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II1275
NCBI Locus TagBTH_RS06525
Name
Replicon chromosome II
Genomic location 1518815 - 1519621 (+ strand)
Transposon Mutants 2 transposon mutants in E264 ATCC 700388
CommentMember of the toxoflavin-like gene cluster

Cross-References

RefSeq YP_439471.1
GI 83717618
Entrez 3846698
GI 83717618
INSDC ABC35507.1
NCBI Locus Tag BTH_RS06525
NCBI Old Locus Tag BTH_II1275
RefSeq YP_439471.1
UniParc UPI0000667861
UniProtKB Acc Q2T5S8
UniProtKB ID Q2T5S8_BURTA
UniRef100 UniRef100_Q2T5S8
UniRef50 UniRef50_Q2T5S8
UniRef90 UniRef90_Q2T5S8

Product

Feature Type CDS
Coding Frame 1
Product Name
transcription regulator LuxR family protein
Synonyms
Evidence for Translation
Charge (pH 7) -1.98
Kyte-Doolittle Hydrophobicity Value -0.224
Molecular Weight (kDa) 29798.7
Isoelectric Point (pI) 6.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 60 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG020777 (305 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II1275

Human Homologs

References

Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase.
Fenwick MK, Almabruk KH, Ealick SE, Begley TP, Philmus B
Biochemistry 2017 Aug 1;56(30):3934-3944
PubMed ID: 28665591